Nice job lads! The old Register design was ok in a retro no-nonsense sort of way, but the new design just looks far cleaner and more modern. It appears that they've added some nice structural changes too, the permalinks are now meaningful rather than being just a jumble of numbers, the page titles carry a hint about the current story - exceedingly useful when one has dozens of browser tabs (or browser windows for you IE victims) open - and they even claim "We're proud that The Register uses valid XHTML and CSS on its pages".
Now, who's next? There's plenty of news organisations with lamentable sites (and a few who still haven't learnt about feeds), it's great to see el Reg leading the way!